Shreejoy Tripathy

Keywords: Neuron Physiology, Single-cell genomics, RNA-seq, Patch-clamp, Patch-seq, Machine learning, Depression, Epilepsy, Alzheimer’s, Cross-species analysis, Collaboration, Neuroinformatics, Bioinformatics, Open-Source Software, Databases, Computational Neuroscience METHODS USED Data Science, Bioinformatics, Neuroinformatics, Machine Learning, Collaboration, Computer Programming Programming languages: R, Python Research Divisions: Brain Research and Integrated Neurophysiology Research Interests: We aim to develop a multi-scale understanding of brain cell type diversity, bridging genetics and gene expression with cell and circuit physiology. We develop machine learning and statistical methods to help neuroscientists translate information at different levels of organization, like gene expression to neuron electrophysiology. Our long-term goal is to better understand the cellular changes that underlie psychiatric and neurological disorders and to ultimately develop approaches that can help guide tailored treatments for mental health patients. Our lab is part of the new Krembil Centre for Neuroinformatics, where we contribute to the building of large-scale computational simulations of the nervous system. We are a computational “dry-lab”, but we collaborate extensively with experimental groups in Toronto and beyond.e