Shoshana Eitan

Dr. Eitan's lab is focused on understanding the biological mechanisms underlying mental and neurological disorders, and to develop improved strategies for prevention and management of these disorders. Recent work in the laboratory is focused on dietary/microbial modulators as related to the prevention and treatment of major depressive disorder (MDD), anxiety, and Parkinson's disease (PD). We are interested in the role of the microbiota-gut-brain axis and the mechanisms by which dietary/microbial modulators affect depression, anxiety, and cognition via modulation of peripheral inflammation and neuroinflammation.

Hailemariam A, Upadhyay S, Oany AR, Tsui WNT, Srivastava V, Sivaram G, Churion K, Chapkin RS, Davidson LA, Eitan S, Cai JJ, Norton R, Safe S. (2026). Brewed Coffee and Its Components Act Through Orphan Nuclear Receptor 4A1 (NR4A1). Nutrients, 18(6):877. Madison CA, Debler RA, Gallegos PL, Hillbrick L, Chapkin RS, Safe S, Eitan S. (2025). 1, 4-dihydroxy-2-naphthoic acid prevents 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced motor function deficits. Behavioural Pharmacology, 36(1):40-46. Hu H, Yuan M, Chen J, Fan T, Nguyen N, Madison CA, Yan T, Xiao Z, Li Y, Eitan S, Zhou H-c, Pellois JP, Wang Y (2024). Pharmacokinetic modeling of solid and hollow gold-coated superparamagnetic iron oxide nanoparticles for brain-targeted therapeutics: prediction and experiment. Advanced Composites a