Robert DeRubeis

Psychopathology and Psychotherapy Specific Research Areas Causes and treatments of mood disorders Research Synopsis In my lab we focus on the processes and outcomes of treatments for depression with the goal of understanding the mechanisms of effective treatments and improving the delivery of these treatments to the patients who are most likely to benefit from them. Currently we are developing methods to identify, for a given patient, which of two or more potentially effective treatments (e.g., medications vs. cognitive therapy for depression) is most likely to lead to symptom improvement. We use a variety of information (demographic, personality, genetic, neuropsychological) to generate differential predictions of response, based on models developed with data from randomized trials. We also are working to identify the specific elements or techniques of cognitive therapy that are most likely to be helpful for a given patient (e.g., with or without personality disorder, co-morbid anxiety) from the discovery of process-outcome relationships that vary across patients who present with different profiles. Professor Robert DeRubeis is no longer accepting new graduate students.