Richard Clark

Dr Clark is an Associate Professor at the School of Biomedical Sciences where he is Head of the Peptide Chemical Biology Lab. He completed his PhD in 2000 at the UQ Chemistry Department studying marine natural products chemistry and chemical ecology with Prof. Mary Garson. He then shifted his research focus towards peptide chemistry, structural biology and drug design when he was recruited to the lab of Prof. David Craik at the IMB. His current research focus is the development of technologies to stabilise peptide therapeutics and the elucidation of the structure/function activity of bioactive peptides. Biological Sciences, Medicinal and biomolecular chemistry, Pharmacology and pharmaceutical sciences

[2026] Molecular basis of diverse ligand recognition and species-specific pharmacology at the complement anaphylatoxin receptor C3aR [2026] Structural basis of complement anaphylatoxin receptor activation by an immunostimulant lead candidate [2026] Molecular mechanisms of naturally encoded signaling bias at the complement anaphylatoxin receptors [2026] The isolated thumb domain of acid‐sensing ion channels forms a minimal folding unit enabling ligand binding studies [2026] The Isolated Thumb Domain of Acid‐Sensing Ion Channels Forms a Minimal Folding Unit Enabling Ligand Binding Studies [2026] C5aR1 inhibition alleviates cranial radiation-induced cognitive decline [2025] Proline hydroxylation and C-terminal amidation in µ-conotoxins increase structural stability and potency at sodium chann