Michael R. Gryk
Associate Professor, Department of Molecular Biology and Biophysics · UConn Health · University of Connecticut
Quick answer: Michael R. Gryk is Associate Professor, Department of Molecular Biology and Biophysics at University of Connecticut. Michael R. Gryk shows an active PhD hiring signal as of 2026-09-11.
⭐ Not accepting lab rotation students at this time for Fall 2025/Spring 2026
Research interests
The focus of our laboratory is structural bioinformatics. We are currently involved in several projects on this topic, mainly the use of NMR spectroscopy as a tool for macromolecular characterization and molecular structure as an aid to bioinformatics.
Particular projects include the development of CONNJUR (connjur.uchc.edu) – an open source integration platform for biomolecular NMR data processing; utilizing non-uniform sampling techniques and the use of maximum entropy methods for spectral reconstruction; and the development of a database of short linear motifs which confer specific functions to proteins (mnm.engr.uconn.edu). NMR studies involve DNA repair proteins of relatively large molecular weight for NMR spectroscopy (20-70 kDa). Current methods to overcome the difficulties inherent in studying these large systems include extensive labeling using stable isotopes and the use of TROSY-based pulse sequences. A critical mission of the lab is the facility approach to NMR, such that as advancements are made, they are tailored for ease-of-use both internally and externally when possible.
Selected publications (since 2023)
NMRhub: An NMR Data Ecosystem Spanning the Complete Data Lifecycle. Journal of molecular biology 2026 Mar; 169769
Scalable cyberinfrastructure for experimental NMR data. Scientific data 2025 Dec;
Evaluating metrics of spectral quality in nonuniform sampling. Journal of Magnetic Resonance Open 2025 Jun; 23: 100187
Pulse, Parse, and Ponder: Using Invisible XML to Dissect a Scientific Domain Specific Language. Proceedings of Balisage: The Markup Conference 2024 2024 Aug; 29
Biological Magnetic Resonance Data Bank. Nucleic acids research 2023 Jan; 51(D1): D368-D376
Frequently asked questions
Is Michael R. Gryk hiring PhD students at University of Connecticut?
Yes. As of 2026-09-11, Michael R. Gryk's faculty page shows a PhD hiring signal: Not accepting lab rotation students at this time for Fall 2025/Spring 2026.
What does Michael R. Gryk research?
The focus of our laboratory is structural bioinformatics. We are currently involved in several projects on this topic, mainly the use of NMR spectroscopy as a tool for macromolecular characterization and molecular structure as an aid to bioinformatics.
Particular projects include the development of
Data last updated: 2026-09-11 · Source: phd-match.com faculty database.
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