Madison L. Doolittle
Assistant Professor, Center for Regenerative Medicine and Skeletal Development · UConn School of Dental Medicine · University of Connecticut
Quick answer: Madison L. Doolittle is Assistant Professor, Center for Regenerative Medicine and Skeletal Development at University of Connecticut. Madison L. Doolittle shows an active PhD hiring signal as of 2026-09-11.
⭐ Not currently accepting lab rotation students
Research interests
We study mechanisms of musculoskeletal aging, senescence, and osteoimmunology within the bone microenvironment. With age, a higher proportion of cells exhibit cellular senescence: a growth-arrested, yet inflammatory state that drives tissue dysfunction. A primary focus of our laboratory is to understand the paracrine effects of senescence with neighboring immune and mesenchymal cells, which may shed light on how senescent cells evade immune clearance and perpetuate age-related diseases.
Selected publications (since 2023)
<a style="color: #336699;" href='http://www.ncbi.nlm.nih.gov/pubmed/41592025' target="_blank">Aged murine bone marrow myeloid and mesenchymal cells develop unique senescence phenotypes.</a>
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<span id="publication-authors">Doolittle, Madison L; Froemming, Mitchell N; Rowsey, Jennifer L; Ruan, Ming; Sapra, Leena; Farr, Joshua N; Monroe, David G; Khosla, Sundeep</span> <span id="publication-journal">The Journal of clinical investigation</span> <span id="publication-year">2026 Jan;</span><span id="publication-volume"></span><span id="publication-issue"></span><span id="publication-pages"></span>
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<a style="color: #336699;" href='http://www.ncbi.nlm.nih.gov/pubmed/41437
Frequently asked questions
Is Madison L. Doolittle hiring PhD students at University of Connecticut?
Yes. As of 2026-09-11, Madison L. Doolittle's faculty page shows a PhD hiring signal: Not currently accepting lab rotation students.
What does Madison L. Doolittle research?
We study mechanisms of musculoskeletal aging, senescence, and osteoimmunology within the bone microenvironment. With age, a higher proportion of cells exhibit cellular senescence: a growth-arrested, yet inflammatory state that drives tissue dysfunction. A primary focus of our laboratory is to unders
Data last updated: 2026-09-11 · Source: phd-match.com faculty database.
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