Jim Janetka
Carl Frieden Distinguished Professor, Professor of Biochemistry and Molecular Biophysics, Professor of Molecular Microbiology · WashU Medicine · Washington University in St. Louis
Quick answer: Jim Janetka is Carl Frieden Distinguished Professor, Professor of Biochemistry and Molecular Biophysics, Professor of Molecular Microbiology at Washington University in St. Louis. Jim Janetka shows an active PhD hiring signal as of 2026-09-11.
⭐ Available to Mentor: PhD Students
Research interests
We are interested in the discovery and development of novel therapeutics for treatment and prevention of cancer and infectious disease. One aim of our current research focuses on the identification of unconventional allosteric inhibitors of the trypsin-like serine proteases, HGFA, matriptase, and hepsin. These proteases are up-regulated in many invasive cancers and regulate the activation of hepatocyte growth factor (HGF) and macrophage stimulating protein (MSP-1). Another aim of our research centers on the developing small-molecule antagonists of the UPEC bacterial adhesion protein FimH for the treatment of urinary tract infections (UTI).
Selected publications (since 2023)
[2026] Inhibitors of membrane associated serine proteases block replication of coronavirus SARS-CoV-2 and influenza virus H1N1
[2026] Towards broad-spectrum antiviral drugs: inhibition of transmembrane serine proteases
[2025] Anthelmintics Derived from the Kinase Inhibitor SGI-1776 for the Treatment of Gastrointestinal Worm Infections
[2025] Ciliated cells promote high infectious potential of influenza A virus through the efficient intracellular activation of hemagglutinin
[2025] Discovery of Human PIM Kinase Inhibitors as a Class of Anthelmintic Drugs to Treat Intestinal Nematode Infections
Frequently asked questions
Is Jim Janetka hiring PhD students at Washington University in St. Louis?
Yes. As of 2026-09-11, Jim Janetka's faculty page shows a PhD hiring signal: Available to Mentor: PhD Students.
What does Jim Janetka research?
We are interested in the discovery and development of novel therapeutics for treatment and prevention of cancer and infectious disease. One aim of our current research focuses on the identification of unconventional allosteric inhibitors of the trypsin-like serine proteases, HGFA, matriptase, and he
Data last updated: 2026-09-11 · Source: phd-match.com faculty database.
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