Jeremy Keown

RNA viruses are a vast group of viruses that infect humans, animals, and plants. Each year, these viruses cause regional epidemics and, at times, large global pandemics. Well-known RNA viruses include the influenza virus, the measles virus, and the Ebola virus. My research focuses on the function of a viral enzyme called the polymerase. The polymerase is particularly important in the lifecycle of the virus as it produces viral mRNA and new copies of viral RNA. In my research group, we employ techniques across scale from atoms to cells to understand the intricate detail of these small molecular machines. By understanding the details of these processes, we aim to develop new antiviral compounds.

Deng, Adrian, Cunnison, Rory, Carrique, Loïc, Günl, Franziska, Pardon, Els, Steyaert, Jan, Duc, David Nguyen, Grimes, Jonathan M., Robb, Nicole C. and Keown, Jeremy R. (2026) Structural and functional characterisation of the Crimean-Congo haemorrhagic fever virus RNA dependent RNA polymerase. Nature Communications . doi:10.1038/s41467-026-74113-w ISSN 2041-1723. (In Press) Alexander, Leila T., Follonier, Océane M., Kryshtafovych, Andriy, Abesamis, Kim, Bibi‐Triki, Sabrina, Box, Henry G., Breyton, Cécile, Bringel, Françoise, Carrique, Loic, d'Acapito, Alessio et al. (2026) Protein target highlights in CASP16 : insights from the structure providers. Proteins: Structure, Function, and Bioinformatics, 94 (1). pp. 25-50. doi:10.1002/prot.70025 ISSN 0887-3585. Yosaatmadja, Yuliana, Ung, Vanessa,