Feliks (Ephraim) Trakhtenberg
Associate Professor, Neuroscience · UConn Health · University of Connecticut
Quick answer: Feliks (Ephraim) Trakhtenberg is Associate Professor, Neuroscience at University of Connecticut. Feliks (Ephraim) Trakhtenberg shows an active PhD hiring signal as of 2026-09-11.
⭐ Accepting Lab Rotation Students: Lab rotation projects revolve around fundamental questions in neuronal development and regeneration in the CNS. We integrate cutting edge molecular, biochemical, genetic, bioinformatics, and translational approaches. Rotation projects involve the following techniques: --Histology and neuroanatomical analysis using confocal microscopy --Rodent CNS in vivo injury mod
Research interests
Our goal is to understand the molecular mechanisms of neuronal development and regeneration, and to utilize gained knowledge in developing translational approaches for repairing injured central nervous system (CNS) circuits. Several species of lower vertebrates have the capacity to regenerate and repair the injured CNS. However, in mammals the ability for CNS self-repair is lost during maturation. The failure of the CNS to regenerate is a major unmet clinical problem, which limits recovery of functions after brain injury, spinal cord injury, white matter stroke, and optic neuropathies. For example, these injuries could disrupt the long distance axonal connections between neurons, and lead to disabilities such as paralysis or blindness. The model system we use to tackle this problem is an injury to the optic nerve in rodents, which is an accepted model of human traumatic optic neuropathy. Furthermore, the approaches which could regenerate axons in this circuit have the potential to repair other CNS circuits as well. Due to the proprietary nature of the research projects in our lab, detailed information about the research program and rotation projects for PhD students is not available publicly. If you are interested in neuroregeneration research, please schedule an appointment with Dr. Trakhtenberg to learn more about open rotation projects.
Selected publications (since 2023)
Journal Articles
Experimental upregulation of Lancl1 promotes axon regeneration after optic nerve injury in vivo.
Lukomska, Agnieszka; Frost, Matthew P; Brady, Jacob; Kearney, Anja; Balaji, Arnav J; D'Souza, Clyde; Trakhtenberg, Ephraim F Experimental neurology 2026 Apr;115789
Vacuolar ATPase subunit Atp6v0c transgene promotes neuroprotection and long-distance axon regeneration in injured retinal ganglion neurons
Kearney, A.; Lukomska, A.; Brady, J.; Damania, A.; Gupta, M.; Trakhtenberg, E.F. Molecular Therapy Nucleic Acids 2026 Apr;In Press
Single-cell transcriptomics-enabled advances in experimental optic nerve axon regeneration research.
Trakhtenberg, E.F. In Bhattacharya. S.K. (Ed.): Proteomics, Multi-Omics and Systems Biology in Optic Nerve Regeneration; Elsevier. 2025 Jan;14:207-2
Frequently asked questions
Is Feliks (Ephraim) Trakhtenberg hiring PhD students at University of Connecticut?
Yes. As of 2026-09-11, Feliks (Ephraim) Trakhtenberg's faculty page shows a PhD hiring signal: Accepting Lab Rotation Students: Lab rotation projects revolve around fundamental questions in neuronal development and regeneration in the CNS. We integrate cutting edge molecular, biochemical, genet.
What does Feliks (Ephraim) Trakhtenberg research?
Our goal is to understand the molecular mechanisms of neuronal development and regeneration, and to utilize gained knowledge in developing translational approaches for repairing injured central nervous system (CNS) circuits. Several species of lower vertebrates have the capacity to regenerate and re
Data last updated: 2026-09-11 · Source: phd-match.com faculty database.
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