Bettina Hansen

Overall research objective is to make a valuable contribution to a better understanding and identification of patients with a chronic or threatening disease who will experience disease progression or may effectively respond to treatment. Of particular focus is development of individualized prediction models of complicated follow-up survival data and dynamic scoring methods to be applied in the daily medical practice. In parallel a major interest is to initiate and coordinate International and National platforms for specialised scientists allowing collaboration across borders for a deeper understanding of specific areas within rare diseases. Another target of her research is the development of new designs for clinical trials particularly in the setting of rare diseases, where standard randomized controlled trials are not feasible and often unethical. This includes investigating surrogate endpoints and use of historical controls in a statistical new framework with high quality barriers.