Murray-Heilig Chair in Molecular Medicine
Professor of Medicine and Genetics and Genome Sciences
Chief, Division of Endocrinology and Metabolism
Director, Center for Molecular Oncology and
Chief Academic Officer, Carole and Ray Neag Comprehensive Cancer Center
Director, Office of Physician-Scientist Career Development · University of Connecticut
Quick answer: Andrew Arnold, MD is Murray-Heilig Chair in Molecular Medicine
Professor of Medicine and Genetics and Genome Sciences
Chief, Division of Endocrinology and Metabolism
Director, Center for Molecular Oncology and
Chief Academic Officer, Carole and Ray Neag Comprehensive Cancer Center
Director, Office of Physician-Scientist Career Development at University of Connecticut. Andrew Arnold, MD shows an active PhD hiring signal as of 2026-09-11.
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Research interests
The most longstanding interest of our laboratory has been in the molecular genetic underpinnings of tumors of the endocrine glands. It was in the context of a search for a parathyroid tumor oncogene lying adjacent to a clonal chromosomal breakpoint that we discovered cyclin D1 (PRAD1). Cyclin D1 has proven to play a key role in cell cycle regulation, and has emerged as a major human oncogene, important in multiple types of tumors including breast cancer and B-cell lymphoma. We are currently pursuing a number of approaches, including the use of transgenic mouse models, to learn more about the precise mechanisms by which cyclin D1 exerts its oncogenic effects. In addition to the cyclin D1 work, we are continuing a major initiative seeking additional genes that contribute to endocrine neoplasia. As an example, we identified the HRPT2 (CDC73) gene as a major factor in the development of malignant parathyroid tumors, a finding that carries important clinical implications.
Selected publications (since 2023)
[2026 Mar] Mutational patterns in a large cohort of parathyroid carcinomas.
[2026 Feb] Evocalcet improved the PTH-calcium setpoint and suppressed parathyroid proliferation in mice model of primary hyperparathyroidism.
[2025 Aug] Multiple endocrine neoplasia type 1 (MEN1): recommendations and guidelines for best practice.
Is Andrew Arnold, MD hiring PhD students at University of Connecticut?
Yes. As of 2026-09-11, Andrew Arnold, MD's faculty page shows a PhD hiring signal: please contact PI to discuss.
What does Andrew Arnold, MD research?
The most longstanding interest of our laboratory has been in the molecular genetic underpinnings of tumors of the endocrine glands. It was in the context of a search for a parathyroid tumor oncogene lying adjacent to a clonal chromosomal breakpoint that we discovered cyclin D1 (PRAD1). Cyclin D1 has
Data last updated: 2026-09-11 · Source: phd-match.com faculty database.
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