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André A. Grassmann

Assistant Professor · UConn Health · University of Connecticut

Quick answer: André A. Grassmann is Assistant Professor at University of Connecticut. André A. Grassmann shows an active PhD hiring signal as of 2026-09-11.

⭐ The Spirochete Research Laboratories offer research opportunities for graduate students, MD/PhD students, postdoctoral fellows, and motivated undergraduate trainees. Ongoing projects include defining gene regulatory networks across theBorreliaenzootic cycle, mapping protein–DNA interactions, and characterizing infection-relevant outer membrane proteins inLeptospira. Trainees are encouraged to deve

Research interests

I am a molecular microbiologist studying how bacterial pathogens sense host environments and remodel gene expression and cell surface architecture to promote infection, persistence, and transmission. My work focuses on spirochetes, includingBorrelia burgdorferi,Leptospira interrogans, andTreponema pallidum, and integrates genetics, transcriptomics, structural biology, and infection-relevant models. A central goal of my research is to define how regulatory responses to host signals generate biologically meaningful phenotypes at the host–pathogen interface, with direct implications for pathogenesis and vaccine development.

Selected publications (since 2023)

[2025] DNA Binding by BosR Controls RpoS-Dependent and -Independent Gene Expression in Borrelia burgdorferi. [2025] Sequence variability of BamA and FadL candidate vaccinogens suggests divergent evolutionary paths of Treponema pallidum outer membrane proteins. [2024] Immunodominant extracellular loops of Treponema pallidum FadL outer membrane proteins elicit antibodies with opsonic and growth-inhibitory activities. [2024] Leptospira interrogans encodes a canonical BamA and three novel noNterm Omp85 outer membrane protein paralog­s. [2023] BosR and PlzA reciprocally regulate RpoS function to sustain Borrelia burgdorferi in ticks and mammals.
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Frequently asked questions

Is André A. Grassmann hiring PhD students at University of Connecticut?
Yes. As of 2026-09-11, André A. Grassmann's faculty page shows a PhD hiring signal: The Spirochete Research Laboratories offer research opportunities for graduate students, MD/PhD students, postdoctoral fellows, and motivated undergraduate trainees. Ongoing projects include defining .
What does André A. Grassmann research?
I am a molecular microbiologist studying how bacterial pathogens sense host environments and remodel gene expression and cell surface architecture to promote infection, persistence, and transmission. My work focuses on spirochetes, includingBorrelia burgdorferi,Leptospira interrogans, andTreponema p

Data last updated: 2026-09-11 · Source: phd-match.com faculty database.

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